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Psilocybia / Chemistry / Psilocin

Compound record

Psilocin

The dephosphorylated congener of psilocybin, identified in 1959.

Molecular formula
C₁₂H₁₆N₂O

01First description

Psilocin was identified by Hofmann and Troxler, reported in Experientia in 1959, the year after the two psilocybin papers by the same group.

This paper is not available in abstract or full text through the indexes consulted here, and is cited for the identification its title reports rather than for its contents.

Sources: [hofmann-1959-psilocin]

02Relationship to psilocybin

A 2022 genetic survey of Psilocybe natural products describes psilocin as the dephosphorylated congener of psilocybin, and identifies psilocybin as the main natural product for which these fungi are known.

Sources: [dorner-2022-psilocybe-genetic-survey]

03Scope of this record

This record covers chemical identity and the published history of the compound. It does not describe effects, preparation or dose, and nothing here is guidance for use.

04References

  1. Dörner S; Rogge K; Fricke J; Schäfer T; Wurlitzer J; Gressler M; Pham D; Manke D; Chadeayne A; Hoffmeister D (2022). Genetic Survey of Psilocybe Natural Products. ChemBioChem 23(14). DOI: 10.1002/cbic.202200249 Source record ↗

    Source class: primary.

    Source verification history
    • metadata: verified · 2026-09-15 · Psilocybia editorial. Verification source

      Bibliographic record retrieved from Crossref. Authors, title, journal, volume, pages and year read directly from that record.

    • doi: verified · 2026-09-15 · Psilocybia editorial. Verification source

      DOI resolved and matched against the Crossref bibliographic record.

    • content: verified · 2026-09-15 · Psilocybia editorial. Verification source

      Abstract inspected via Europe PMC. Full text was not retrieved; claims drawn from this source are scoped to the abstract.

  2. Hofmann A; Troxler F (1959). Identifizierung von Psilocin. Experientia 15(3), 101-102. DOI: 10.1007/bf02166696 Source record ↗

    Source class: primary.

    Source verification history
    • metadata: verified · 2026-09-15 · Psilocybia editorial. Verification source

      Bibliographic record retrieved from Crossref. Authors, title, journal, volume, pages and year read directly from that record.

    • doi: verified · 2026-09-15 · Psilocybia editorial. Verification source

      DOI resolved and matched against the Crossref bibliographic record.

    • content: unavailable · 2026-09-15 · Psilocybia editorial. Verification source

      No abstract or full text available through the indexes consulted. Only the bibliographic record and title were inspected, so this source supports the fact of its own report and not any detail within it.